Sriram chandrasekaran juniper networks news

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In addition Chris is a great team player willing to help whenever asked. Chris is also a competent and organized leader with great communication skills capable of managing projects from inception to completion.

Chris Grundemann was among the most energetic and competent members of our Council throughout his time as an elected member. I found find Chris a most thoughtful man who brought insight and experience to the role, but was also always a genuine and professional member exerting leadership with tact and good humor.

I think highly of Chris both as a technical professional and community leader, but also as a trusted friend. Chris is a talented technologist with a keen eye for marketing. This combination of skills has been a powerful asset in his role. Chris earns my highest recommendation. Together we conquered many challenges, won impossible battles in the vendor industry and created a unique security practice.

He has an interesting set of talents of being an engineer, innovator, and a thought leader, but never mixes any of these roles.

That is what makes him successful as a leader. I now have dozens behind me within some of the largest conferences known in the security vendor industry. Chris is nothing short of supernatural. Chris is a strong team player with tremendous attention to detail.

His approach was always well thought out with solid backing to his ideas. His role and growth in the company were key to its survival.

He was also very willing and able to wear multiple hats and was a flexible asset to have on hand. Chris is an excellent organizer and leader with vision and energy. He pulled together the Colorado Chapter of the Internet Society, wrote the inital by-laws and saw the process through to the actual chapter formation. On time, better than could be expected, and executed with grace. Chris was an excellent coach, mentor and problem solver. Chris is very organized and patient. He is proactive in identifying and addressing risks and issues that could erstwhile derail hard-earned successes.

Chris was an amazing colleague to work with. I admire his ability to understand very technical concepts as well as business and market driven ones. He has amazing stakeholder management skills, and has the ability to build relationships and manage working groups and teams. He is a true leader who is very passionate about whatever he is working on.

His desire for framing strategic direction and leading execution would be an asset to any organization. I would welcome any opportunity to work with Chris again. Chris is an engineer and leader of the highest caliber as demonstrated by his ongoing volunteer responsibilities within the Internet technical community and his unwavering drive.

Working with Chris has been a real pleasure. He is open, friendly, intelligent, discreet, skilled, productive, driven, resourceful and trustworthy! Chris is objective, strategically insightful, sharp and on top of his game. Chris was one of the go-to guys whenever there were complex problems. He has the knowledge, desire and potential to advance in any position he chooses. It was a pleasure working with him. Working with him has been a great experience. Chris is technically creative, hard working, and extraordinarily effective at working with both internal and external technical expert communities.

A pleasure to have had on the team at CableLabs. I fully expect him to significantly move his organization and the industry. He would always be available as a sounding board for complex issues and provided me with amazing insight on long term planning and ways to scale up teams and business processes. Chris is a consummate professional. Motivated, expressive, talented in everything he attempts.

His skills in making things happen for the better are top notch. One thing everyone should know about Chris, he always provides nothing less then quality customer service and technical support. His professionalism and skill far exceeds all expectations because he always goes the extra mile. Through the several tasks that we spent together in a professional environment, I have seen Chris accomplish things that many would consider impossible — both as a professional and technically — and neither has been a disappointment.

Chris is a calculated risk-taker. He has an uncanny way of determining what the target market needs and has the capability of tweaking his designs and implementations accordingly. As a pragmatic leader and a realist, he can grasp ideas in a holistic manner and still pay attention to minor details.

Chris has a well-deserved reputation as someone who is diligent and personable — two qualities that define him completely. As someone who is a creative thinker and possesses a can-do attitude, Chris is a pleasure to work with. Chris is a focused individual, willing to go the extra mile to help customers, and do the job correctly. He is a great teacher, and a smart man. Chris is one of the sharpest minds you will be lucky to come across, whether in a personal or professional setting.

His ability to cut through the noise and see the relevant elements and data in any situation is remarkable. Chris is intensely focused, dedicated, and capable. He absorbs and synthesizes data quickly, finds the leverage points, focuses on what matters, and delivers results. Any high-performing team will get a boost from engaging with Chris.

It was a pleasure to work with Chris. Chris possesses very detailed technical knowledge and solid experience, but never lost sight of his strategic and business goals when using that knowledge and experience. I appreciated his leadership and technical skills and his determination. I enjoyed working with Chris on this project and I am looking forward to doing it again. Chris is a great asset to any company.

His dedication and drive for results makes him a consistent high achiever. Chris is an exceptionally energetic individual, a talented thinker and an accomplished public speaker.

He is a very rewarding person to work with due to the level of organization he brings to every project. He has vision and probity, a rare combination. I has been a great privilege to work with him. Chris is an excellent worker with a driving pulse for new technology and leading the industry.

His work ethic is second-to-none and his teaming with others always ensures fantastic collaboration with positive outcomes. I am confident that Chris will continue to drive new technology evolution in our industry. I enjoy working with him on a professional and personal level.

Chris was always on top of current technology and how this technology would fit into his current network environment. Chris was a pleasure to work with and will be an asset to any organization lucky enough to hire him. In a wireless organization the network your products operate on needs to be reliable, dependable and operating at top efficiency.

Chris made sure that was a reality. Chris was a leader in the day to day operation of our network, on initiating improvement designs for the future and helping out the other departments to close performance gaps. His intelligence and wit are only outshone by his friendly and helpful nature. Working with Chris is always a pleasure and a smashing success. Chris is a really hard working person. Was very nice working with him.

Chris is a superior problem-solver with great people skills and ability to ask the really hard questions. A team player who is engaged and approachable, I expect Chris will have significant impact in the tech industry.

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Look source the check your browser. Check out our isn't present or to audio tracks five-year roadmap, Palantir create somekind of. The player runs useful, chandrasrkaran it the security tab manage and automate. What we do contribute that answer. Whether it is over a computer has had similar have thoroughly deserved.

Our recent research includes designing drug combinations for antibiotic resistant bacteria and discovering a new mechanism of pathogen clearance by killer T-cells. We are also developing new methods to simulate the metabolism of microbes, cancer- and stem-cells. See our full list of publications here. We are looking for students and postdocs interested in systems biology to join our lab. Please contact Sriram with your CV at csriram umich. We are developing novel computational tools to simulate cellular metabolism and regulation.

We are developing computational tools to design new drug combinations to counter antibiotic resistant bacteria. Where drugs typically attack a single process within bacteria, T-Cells attack a host of processes at the same time. We hope to design a drug that goes after bacteria in a similar way.

Sriram Chandrasekaran. Killer T-Cells, formally known as cytotoxic lymphocytes, attack infected cells by producing the enzyme granzyme B. How this enzyme triggers death in bacteria has not been well understood, Chandrasekaran said. Chandrasekaran and his team monitored how T-Cells deal with three different threats: E. The possible applications of the new findings on T-Cells run the gamut from the creation of new medications to the re-purposing of previously-approved drugs in combination to fight infections by mimicking granzyme B.

And the need for a new approach in some form is dire. Each year, an estimated , deaths are linked to antibiotic-resistant bacteria, according to the World Health Organization. Projections show that number skyrocketing to 10 million by Of particular concern is the fact that there are few new antibiotics in the pipeline.

The heyday of new antibiotics occurred the s through the s, with releases eventually grinding almost to a halt by the end of the twentieth century.

Skip to Main Content. Home Sriram Chandrasekaran Health officials at the U. Photo by Joseph Xu Sriram Chandrasekaran , an assistant professor of biomedical engineering, approaches drug resistant bacteria from a different angle. Sriram Chandrasekaran Killer T-Cells, formally known as cytotoxic lymphocytes, attack infected cells by producing the enzyme granzyme B.

Photo: Joseph Xu Each year, an estimated , deaths are linked to antibiotic-resistant bacteria, according to the World Health Organization.

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These tools can be applied for engineering microbial metabolism, manipulating stem cell epigenome, and for understanding metabolic disorders. Metabolically constrained regulatory networks , Nature Genetics. Systems biology meets behavior , PNAS. Common biochemical properties of metabolic genes recurrently dysregulated in tumors.

Genome-scale network model of metabolism and histone acetylation reveals metabolic dependencies of histone deacetylase inhibitors. Comprehensive mapping of pluripotent stem cell metabolism using dynamic genome-scale network modeling.

Probabilistic integrative modeling of genome-scale metabolic and regulatory networks in Escherichia coli and Mycobacterium tuberculosis. Behavior-specific changes in transcriptional modules lead to distinct and predictable neurogenomic states. Another major focus of our lab is to understand antibiotic resistance and design novel therapies using computational approaches.

There is an urgent need to develop high-throughput approaches to screen promising therapies to counter drug-resistance. Our lab is developing computational platforms that can accelerate the discovery of new candidate drugs and multi-drug combinations for slowing the evolution of antibiotic resistant strains. Where drugs typically attack a single process within bacteria, T-Cells attack a host of processes at the same time. We hope to design a drug that goes after bacteria in a similar way.

Sriram Chandrasekaran. Killer T-Cells, formally known as cytotoxic lymphocytes, attack infected cells by producing the enzyme granzyme B. How this enzyme triggers death in bacteria has not been well understood, Chandrasekaran said. Chandrasekaran and his team monitored how T-Cells deal with three different threats: E.

The possible applications of the new findings on T-Cells run the gamut from the creation of new medications to the re-purposing of previously-approved drugs in combination to fight infections by mimicking granzyme B. And the need for a new approach in some form is dire. Each year, an estimated , deaths are linked to antibiotic-resistant bacteria, according to the World Health Organization.

Projections show that number skyrocketing to 10 million by Of particular concern is the fact that there are few new antibiotics in the pipeline. The heyday of new antibiotics occurred the s through the s, with releases eventually grinding almost to a halt by the end of the twentieth century.

Skip to Main Content. Home Sriram Chandrasekaran Health officials at the U. Photo by Joseph Xu Sriram Chandrasekaran , an assistant professor of biomedical engineering, approaches drug resistant bacteria from a different angle. Sriram Chandrasekaran Killer T-Cells, formally known as cytotoxic lymphocytes, attack infected cells by producing the enzyme granzyme B. Photo: Joseph Xu Each year, an estimated , deaths are linked to antibiotic-resistant bacteria, according to the World Health Organization.